Postdoc Researcher in Liver Models for Toxicity Testing

We are looking for a motivated Postdoc with a strong background in advanced human cell culture systems, including organoids, and in molecular toxicology.

Your duties

• Development of induced pluripotent stem cell (iPSC)-derived liver models, including organoids derived of hepatocytes and non-parenchymal cells
• Characterisation of functional phase I and II metabolism
• Data analysis and integration of several toxicology assays, including Seahorse bioanalyser (mitochondria toxicity) and transcriptomics datasets
• High Content Imaging
• Publish scientific articles and present research results at conferences;
• Supervision of MSc and BSc students and co-supervision of PhD candidates
• Collaborate within the team and with other international researchers

Requirements:

• PhD obtained within the last 5 years within the discipline of either toxicology, pharmacology, cell -or developmental-biology or a related discipline;
• Strong expertise in 3D human cell culture and iPSC, ideally with liver models
• Background in toxicology and mechanistic assays
• Aptitude for data handling and analysis; Transcriptomics analysis is a plus
• Experience with analytical methods (LC-MS) is an advantage
• Good communication, organizational and social skills;
• High proficiency in speaking and writing in the English language;
• Team player with the ability to work independently;
• Strong motivation for scientific research

As a university, we strive for equal opportunities for all, recognising that diversity takes many forms. We believe that diversity in all its complexity is invaluable for the quality of our teaching, research and service. We are always looking for talent with diverse backgrounds and experiences. This also means that we are committed to creating an inclusive community so that we can use diversity as an asset.

We realise that each individual brings a unique set of skills, expertise and mindset. Therefore we are happy to invite anyone who recognises themselves in the profile to apply, even if you do not meet all the requirements.

Salary Benefits:

A challenging position in a socially engaged organisation. At VU Amsterdam, you contribute to education, research and service for a better world. And that is valuable. So in return for your efforts, we offer you:

• a salary of minimum € 3.226,00 (Scale 10) and maximum € 5.090,00 (Scale 10) gross per month, on a full-time basis. This is based on UFO profile Researcher 4. The exact salary depends on your education and experience.
• a position for at least 0.8 FTE. Your employment contract will initially last 1 year.

We also offer you attractive fringe benefits and regulations. Some examples:

• A full-time 38-hour working week comes with a holiday leave entitlement of 232 hours per year. If you choose to work 40 hours, you have 96 extra holiday leave hours on an annual basis. For part-timers, this is calculated pro rata.
• 8% holiday allowance and 8.3% end-of-year bonus
• space for personal development
• a wide range of sports facilities which staff may use at a modest charge
• discount on (and occasionally exclusive access to) theater performances and courses at the Griffioen Cultural Center

De Boelelaan 1108